Pharmacokinetics of Propofol in step down intravenous injection.
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چکیده
منابع مشابه
Pharmacokinetics of tetracycline hydrochloride after single intravenous injection in dogs
Six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. Blood samples were collected before and at various time intervals after the administration of the drug. Serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. Non...
متن کاملpharmacokinetics of tetracycline hydrochloride after single intravenous injection in dogs
six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. blood samples were collected before and at various time intervals after the administration of the drug. serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. non...
متن کاملAnalgesic effects of palonosetron in the intravenous propofol injection
BACKGROUND Propofol is a good induction agent, but it has the disadvantage of causing pain on intravenous injection. The incidence of propofol-induced pain is approximately 70%. Palonosetron is a novel second-generation 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist. We presumed that palonosetron would be effective in reducing the occurrence of propofol-induced pain based on similar mec...
متن کاملEfficacy of intravenous acetaminophen and lidocaine on propofol injection pain.
BACKGROUND Different methods and propofol formulations have been used to decrease propofol injection pain, but it remains an unresolved problem. We aimed to investigate the effect of i.v. acetaminophen pretreatment on the propofol injection pain. METHODS One hundred and fifty ASA I-II patients undergoing general anaesthesia were randomly allocated into three groups. A 20-gauge catheter was in...
متن کاملPharmacokinetics of m-nifedipine in rabbits after intravenous injection.
AIM To study the dose effects on pharmacokinetics of m-Nif. METHODS Fifteen rabbits were divided into 3 groups receiving i.v. m-Nif 0.5, 1, and 2 mg.kg-1. Plasma levels of m-Nif were determined with HPLC method. RESULTS The concentration-time data were fitted with 2-compartment model. After i.v. 1 mg.kg-1, the parameters were: Vd = 0.37 +/- 0.10 L.kg-1, T1/2 alpha = 6.4 +/- 2.9 min, T1/2 be...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1998
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.29.257